Catherine Marcinkiewcz, Ph.D., M.S.
Associate Professor
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About Catherine Marcinkiewcz
Catherine Marcinkiewcz, Ph.D., M.S., joined the UF College of Pharmacy in May 2025. Her lab is currently addressing fundamental questions in neurobiology that have direct relevance for human disease. For instance, how do genes interact with the environment to shape circuit function and behavior in neurological disorders and how can we harness that knowledge to develop more effective treatments? The serotonin system is the central focus of the lab, given its complex role in human psychiatric and neurodevelopmental disorders. We are currently investigating how environmental factors like stress, alcohol, and the use of antidepressant drugs can alter serotonin neurons in the dorsal raphe and their efferent projections, and how this contributes to stress-related disorders and neurodegenerative disease
Teaching Profile
Courses Taught
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GMS7794 – Neuroscience Seminar
College of Medicine
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PHA6512L – Experiential Research Training in Pharmacodynamics
College of Pharmacy
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PHA6521C – Research Techniques in Pharmacodynamics
College of Pharmacy
Publications
Academic Articles
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Impact of adolescent ethanol binge on serotonin signaling and pain sensitivity post-withdrawal.
- Journal
- Alcohol (Fayetteville, N.Y.).
- Volume/Issue
- 129:58-68
- [DOI]
- 10.1016/j.alcohol.2025.09.001.
- [PMID]
- 40939668.
-
The superficial tufted and mitral cell output neurons of the mouse olfactory bulb have dual roles in insulin sensing.
- Journal
- bioRxiv : the preprint server for biology.
- [DOI]
- 10.1101/2025.04.15.648999.
- [PMID]
- 40666896.
-
Mechanistic intersections between migraine and major depressive disorder.
- Journal
- The journal of headache and pain.
- Volume/Issue
- 26(1)
- [DOI]
- 10.1186/s10194-025-02097-x.
- [PMID]
- 40634879.
-
Involvement of a serotonin/GLP-1 circuit in adolescent isolation-induced diabetes.
- Journal
- bioRxiv : the preprint server for biology.
- [DOI]
- 10.1101/2023.06.12.544498.
- [PMID]
- 37398179.
-
Modulation of OCT3 expression by stress, and antidepressant-like activity of decynium-22 in an animal model of depression.
- Journal
- Pharmacology, biochemistry, and behavior.
- Volume/Issue
- 131:33-41
- [DOI]
- 10.1016/j.pbb.2015.01.004.
- [PMID]
- 25597272.
-
Corticotropin-releasing factor within the central nucleus of the amygdala and the nucleus accumbens shell mediates the negative affective state of nicotine withdrawal in rats.
- Journal
- Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
- Volume/Issue
- 34(7):1743-52
- [DOI]
- 10.1038/npp.2008.231.
- [PMID]
- 19145226.
-
Social defeat stress potentiates thermal sensitivity in operant models of pain processing.
- Journal
- Brain research.
- Volume/Issue
- 1251:112-20
- [DOI]
- 10.1016/j.brainres.2008.11.042.
- [PMID]
- 19059227.
-
The effects of buprenorphine on fentanyl withdrawal in rats.
- Journal
- Psychopharmacology.
- Volume/Issue
- 191(4):931-41
- [PMID]
- 17211652.
Grants
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Alcohol-Induced Metabolome-Epigenome Dysfunction and Alzheimers Disease Risk
Active
- Role:
- Other
- Funding:
- NATL INST OF HLTH NIAAA
-
Alcohol and the Serotonin System in the Progression of Alzheimer’s Disease
Active
- Role:
- Principal Investigator
- Funding:
- NATL INST OF HLTH NIAAA
-
Sleep and affective disturbances in the etiology of Alzheimer’s disease
Active
- Role:
- Principal Investigator
- Funding:
- NATL INST OF HLTH NIA
-
Alcohol Use as a Moderating Factor in Serotonergic Neurodegeneration in the Early Stages of Alzheimer’s Disease
Active
- Role:
- Principal Investigator
- Funding:
- US ARMY MED RES ACQUISITION
Contact Details
- Business:
- (352) 594-1403
- Business:
- saffron@ufl.edu
- Business Mailing:
-
PO Box 100487
GAINESVILLE FL 32610 - Business Street:
-
1345 CENTER DR
GAINESVILLE FL 32611